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段金友 
发布时间:2016-04-15  浏览次数:

  一、个人简介

  段金友,西北农林科技大学理学院三级教授、博士生导师。2011年入选陕西省‘百人计划’特聘教授;2012年入选首批中国科学院交叉创新团队;2013年入选教育部‘新世纪优秀人才支持计划’。

  2003.7获得中国科学院上海药物研究所博士学位;2003.11至2010.3先后在美国约翰·霍普金斯大学、哈佛大学医学院从事博士后研究,于2010.4哈佛大学聘为Instructor in Medicine。

  现为第五届中国生物化学与分子生物学会复合糖专业委员会委员。在细胞子刊Cell host & microbe、综合性期刊PNA S和自然旗下的Scientific Reports、Glycobiology等杂志上发表SCI论文四十余篇。

  二、在研科研课题(主持)

  国家自然科学基金面上项目(NSFC31570799);

  国家自然科学基金面上项目(NSFC31270860);

  教育部新世纪人才支持计划(NCET-13-0480);

  上海中医药大学合作项目(K332021201).

  三、研究领域

  药用中药(食品)多糖的结构与功能

  糖载体药物的设计及活性评价

  四、开设课程

  《植物资源化学》、《糖生物学》

  五、主要学术论文

  1.Haibo Mu, Jiangjiang Tang, Qianjin Liu, Chunli Sun, Tingting Wang, Jinyou Duan*.  Potent Antibacterial Nanoparticles against Biofilm and Intracellular Bacteria. Scientific Reports. 2016,6:18877.

  2.Haibo Mu, Qianjin Liu, Hong Niu,Yuelin Sun, Jinyou Duan*. Gold nanoparticles make chitosan–streptomycin conjugates effective towards Gram-negative bacterial biofilm. RSC Advances. 2016,6, 8714-8721.

  3.Qianjin Liu, Haibo Mu, Chunli Sun, Jinyou Duan*.  High specific determination of gentamicin by induced collapse of Au-lipid capsule. RSC Advances. RSC Advances, 2016, 6, 14483-14489.

  4.Haibo Mu, Qianjin Liu, Hong Niu, Dongdong Wang, Jiangjiang Tang*, Jinyou Duan*. Autophagy Promotes DNA-protein Crosslink Clearance. Mutation Research - Genetic Toxicology and Environmental Mutagenesis.2016, 21-25.

  5.Hong Niu, Dan Song, Haibo Mu, Wuxia Zhang, Feifei Sun, Jinyou Duan*.Investigation of three lignin complexes with antioxidant and immunological capacities from Inonotus obliquus. International Journal of Biological Macromolecules. 2016,86:587-593. 

  6.Wuxia Zhang, Dongqi Dong, Peng Li, Dongdong Wang, Haibo Mu, Hong Nu, Jinyou Duan*. Novel pH-sensitive polysialic acid based polymeric micelles for triggered intracellular release of hydrophobic drug. Carbohydrate Polymers. 2016,139:75-81. 

  7.Wuxia Zhang, Peng Li, Dan Song, , Hong Nu, Shansong Shi,Shunchun Wang*, Jinyou Duan*.Structural characterization and biological activities of two α-glucans from Radix Paeoniae Alba. Glycoconjugate Journal. 2016 Jan 8. [Epub ahead of print].

  8.Wuxia Zhang, Dan Song,Dan Xu, Tingting Wang, Lu Chen, Jinyou Duan*. Characterization of polysaccharides with antioxidant and immunological activities from Rhizoma Acori Tatarinowii. Carbohydrate Polymers. 2015,133:154-62.

  9.Dongdong Wang, Wuxia Zhang, Tingting Wang, Na Li, Haibo Mu, Jiwen Zhang, Jinyou Duan*. Unveiling the Mode of Action of Two Antibacterial Tanshinone Derivatives International Journal of Molecular Sciences 2015, 16(8), 17668-17681.

  10.Wuxia Zhang, Feifei Sun, Hong Niu, Qingjie Wang, Jinyou Duan*.Mechanistic insights into cellular immunity of chondroitin sulfate A and its zwitterionic N-deacetylated derivatives. Carbohydrate Polymers. 2015,123:331-8.

  11.Qingjie Wang, Haibo Mu, Lin Zhang, Dongqi Dong, Wuxia Zhang, Jinyou Duan*. Characterization of two water-soluble lignin metabolites with antiproliferative activities from Inonotus obliquus. International Journal of Biological Macromolecules.2015,74:507-14.

  12.Qianjin Liu, Hong Niu, Wuxia Zhang, Haibo Mu, Chunli  Sun,Jinyou Duan*. Synergy among thymol, eugenol, berberine, cinnamaldehyde and streptomycin against planktonic and biofilm-associated food-borne pathogens. Letters in Applied Microbiology. 2015,60(5):421-30.

  13.Lin Zhang, Wuxia Zhang, Qingjie Wang, Dongdong Wang, Dongqi Dong, Haibo Mu, Xinshan Ye*, Jinyou Duan*. Purification, antioxidant and immunological activities of polysaccharides from Actinidia Chinensis roots. International Journal of Biological Macromolecules.2015, 72: 975-983.

  14.Wuxia Zhang, Haibo Mu, Dongdong Wang, Amin Zhang, Jinyou Duan*. Alteration in Immune Responses towards N-deacetylation of Hyaluronic Acid. Glycobiology. 2014, 24(12):1334-42.

  15.Haibo Mu, Fan Guo, Hong Niu, Qingjie Wang, Shunchun Wang, Jinyou Duan*. Chitosan Improves Anti-Biofilm Efficacy of Gentamicin through Facilitating Antibiotic Penetration. International Journal of Molecular Sciences. 2014, 15(12), 22296-22308.

  16.Guoting Cui, Wuxia Zhang, Qingjie Wang, Amin Zhang, Haibo Mu, Hongjing Bai, Jinyou Duan*. Extraction optimization, characterization and immunity activity of polysaccharides from Fructus Jujubae. Carbohydrate Polymers. 2014,111:245-55.

  17.Haibo Mu, Amin Zhang, Lin Zhang, Hong Niu, Jinyou Duan* Inhibitory effects of chitosan in combination with antibiotics on Listeria monocytogenes biofilm. Food Control. 2014, 38:215-220.

  18.Amin Zhang; Haibo Mu; Wuxia Zhang; Guoting Cui; Jie Zhu; Jinyou Duan*. Chitosan coupling makes microbial biofilms susceptible to antibiotics. Scientific Reports. 2013,3:3364.

  19.Vincent L. Chen,Neeraj K. Surana,Jinyou Duan*,Dennis L. Kasper*. Role of murine intestinal interleukin-1 receptor 1-expressing lymphoid tissue inducer-like cells in salmonella infection. PloS One. 2013, 8(6):e65405.

  20.Ying Wang, Jianping Fang, Xinyan Ni, Jie Li, Qin Liu, Qun Dong, Jinyou Duan*, and Kan Ding*.Inducement of Cytokine Release by GFPBW2, a Novel Polysaccharide from Fruit Bodies of Grifola frondosa, through Dectin-1 in Macrophages. Journal of Agricultural and Food Chemistry. 2013,61(47):11400-9.

  21.Guoting Cui, Wuxia Zhang, Amin Zhang, Haibo Mu, Hongjin Bai, Jinyou Duan*, Cuiyun Wu*.Variation in antioxidant activities of polysaccharides from Fructus Jujubae in South Xinjiang area.International Journal of Biological Macromolecules. 2013, 57, 278– 284.

  22.Wuxia Zhang, Haibo Mu, Amin Zhang, Guoting Cui, Hua Chen, Jinyou Duan*, Shunchun Wang*. A decrease in moisture absorption-retention capacity of N-deacetylation of hyaluronic acid. Glycoconjugate Journal. 2013, 30(6):577-83.

  23.Haibo Mu, Amin Zhang, Wuxia Zhang, Guoting Cui, Shunchun Wang*, Jinyou Duan*. Antioxidative Properties of Crude Polysaccharides from Inonotus obliquus. International Journal of Molecular Sciences. 2012, 13(7): 9194-9206.

  24.Xue Xu, Wuxia Zhang, Chao Huang, Yan Li, Hua Yu, Yonghua Wang*, Jinyou Duan*, Yang Ling. A Novel Chemometric Method for the Prediction of Human Oral Bioavailability. International Journal of Molecular Sciences. 2012, 13(6): 6964-6982.

  25.Jinyou Duan* and Dennis L. Kasper. Regulation of T cells by gut commensal microbiota. Current Opinion in Rheumatology. 2011, 23(4):372-6.

  26.Jinyou Duan* and Dennis L. Kasper*. Oxidative depolymerization of polysaccharides by reactive nitrogen/oxygen species. Glycobiology. 2011, 21(4): 401-409.

  27.Jinyou Duan, Hachung Chung, Erin Troy, Dennis L. Kasper*. Microbial colonization drives expansion of IL-1 receptor 1 expressing and IL-17 producing γ/δ T cells. Cell host & microbe. 2010, 7(2): 140-150.

  28.Jinyou Duan. Fikri Y. Avci, Dennis L. Kasper*. Microbial carbohydrate depolymerization by antigen-presenting cells: deamination prior to presentation by the MHCII pathway. PNAS. 2008, 105(13): 5183-8.

  六、联系方式

  通讯地址:西北农林科技大学理学院

  邮编:712100

  电话:18792670650

  邮箱:jduan@nwsuaf.edu.cn

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