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陈红英  
发布时间:2016-04-15  浏览次数:

  

  个人简介

  
陈红英 ,女,博士,教授,1970年6月出生。1988-1992年,中国农业大学动物生理学与生物化学专业本科;1992-1998年,中国农业大学动物生理学与生物化学专业硕博连读;1998-2000年,中国科学院发育生物学研究所,博士后;2000-2009年,英国雷丁大学(University of Reading),Research fellow。2009年9月到西北农林科技大学生命科学学院工作,入选2009年教育部新世纪优秀人才支持计划。

  
研究方向

  
动物病毒(如PRRSV, AcMNPV)蛋白的结构功能,病毒-宿主互作关系

  
发表论文

  
发表科研论文近30篇。代表性论文:

  
1. Liu L, Lear Z, Hughes DJ, Wu W, Zhou E, Whitehouse A,Chen H*, Hiscox JA* Resolution of the cellular proteome of the nucleocapsid protein from a highly pathogenic isolate of porcine reproductive and respiratory syndrome virus identifies PARP-1 as a cellular target whose interaction is critical for virus biology. Veterinary Microbiology 2015, 176(1-2): 109-119.

  
2. Fang W, Peng K, Tian J, Xu X, Zhou E, Chen H* Immune response to Fc tagged GP5 glycoproteins of porcine reproductive and respiratory syndrome virus. Viral Immunology 2014, 27 (7): 343—349.

  
3. Liu B, Wang R, Wu F, Xu X, Chen H* Rapid production of HIV-1 neutralizing antibodies in baculovirus infected insect cells. Protein Expression and Purification 2014, 99:87-93.

  
4. Xu X, Chen Y, Zhao Y, Liu X, Dong B, Jones IM,Chen H* Baculovirus superinfection: A probable restriction factor on the surface display of proteins for library screening. Plos One 8(1): e54631, 2013.

  
5. Hassall M, Page M, Robinson M, Jeffs S, Jones IM, Chen H, Seaman M, Ferguson D, Almond N*The production, characterisation and application of monoclonal antibodies generated by immunisation with HIV-1 Cclade rgp140 envelope protein. Journal of Virological Methods 2013 Aug 23;194(1-2):89-93

  
6. Kong L,SheppardNC, Stewart-JonesGBE,RobsonCL,Chen H , XuX, KrashiasG, ScanlanCBCN, KwongPD, JeffsSA, JonesIMand SattentauQJ* .Expression system-dependent modulation of HIV-1 envelope glycoprotein antigenicity and immunogenicity.J. Mol. Biol. 2010 Oct 403:131-147.

  
7.Chen H , Xu X, Lin HH, Chen SH, Forsman A, Chapman MA, Jones IM* . Mapping the immune response to the outer domain of a human immunodeficiency virus-1 clade C gp120. J. Gen. Virol. 2008 Oct;89(Pt 10):2597-2604

  
8. Chen H , Xu X, Jones IM* . Immunogenicity of the outer domain of a HIV-1 clade C gp120.Retrovirology 2007; 4: 33.

  
9. Chen H , Xu X, Bishop A, Jones IM* . Reintroduction of the 2G12 epitope in an HIV-1 clade C gp120. AIDS. 2005 May 20;19(8):833-5.

  
10. Chen H , Gill A, Dove BK, Emmett SR, Kemp CF, Ritchie MA, Dee M, Hiscox JA* . Mass spectroscopic characterization of the coronavirus infectious bronchitis virus nucleoprotein and elucidation of the role of phosphorylation in RNA binding by using surface plasmon resonance. J Virol. 2005 Jan;79(2):1164-79.

  
11. Chen H , Coote B, Attree S, Hiscox JA*. Evaluation of a nucleoprotein-based enzyme-linked immunosorbent assay for the detection of antibodies against infectious bronchitis virus. Avian Pathol. 2003 Oct;32(5):519-26.

  
12. Chen H , Wurm T, Britton P, Brooks G, Hiscox JA*. Interaction of the coronavirus nucleoprotein with nucleolar antigens and the host cell. J Virol. 2002 May;76(10):5233-50.

  
13. Chen HY , Zhou Q, Zhang MF, and Giambrone JJ*.Sequence Analysis of the VP2 Hypervariable Region of Nine Infectious Bursal Disease Virus Isolates from Mainland China. Avian Diseases 42:762-769, 1998.

  
专著章节:

  
Silvia Loureiro, Elena Robinson,Hongying Chen, Pongsathon Phapugrangkul, Camilo Colaco, Ian M Jones Chapter 3: Virus glycoproteins tagged with the human Fc domain as second generation vaccine candidates. Innovation in Vaccinology ISBN 978-94-007-4542-1, 2012

  
专利:

  
陈红英等,申请号:201310088900.1

  
五、联系方式

  
联系地址:712100 陕西杨凌西北农林科技大学生命学院

  
电子邮件:chenhy@nwsuaf.edu.cn

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